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The Cancer Genome Atlas TCGA, a groundbreaking cancer genomics initiative, systematically analyzed over 20,000 primary cancer and corresponding normal samples from 33 distinct cancer types. This collaborative effort, which was jointly initiated by the National Cancer Institute NCI and the National Genome Research Institute in 2006, assembled an impressive team of researchers across a multitude of fields and institutions.
Over the ensuing decade, TCGA amassed an extensive data repository amounting to over 2.5 petabytes. This wealth of genomic, epigenomic, transcriptomic, and proteomic information has already improved our capabilities for diagnosing, treating, and preventing cancer. Most crucially, this publicly avlable dataset will continue to be accessible to the research community worldwide.
TCGA's Impact on Cancer Research
TCGA has revolutionized our comprehension of cancer by elucidating overarching themes across multiple tumor types. The program has uncovered patterns in cell origin, oncogenic processes, and signaling pathways through its Pan-Cancer Atlas publication, which was released upon the project's in 2018.
Accessing TCGA Data
Researchers can now access this comprehensive dataset via the Genomic Data Commons' Data Portal. The portal offers not only a vast trove of data but also integrated web-based analysis and visualization tools designed to facilitate research.
Cancer Types Studied by TCGA
An outline detling which cancers were selected for study, based on that guided the program's selection process.
TCGA Computational Tools
Insights into several computational software and analytical resources developed during the project, including algorithms for data processing, visualization, and more.
TCGA Molecular Characterization Platforms
Descriptions of each technology platform employed by TCGA, alongside supplementary documentation to d understanding.
TCGA Timeline and Milestones
A chronological summary of pivotal events leading up to TCGA's launch in 2006 as well as significant milestones throughout the program's history.
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20 Comprehensive Cancer Genomics Initiative National Cancer Institutes TCGA Project 000 Primary Cancer Samples Analysis Pan Cancer Atlas Publication Release Accessible Publicly Available Dataset Cancer Research Data Portal Navigation